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Symbol
Name
ID

Hax1
HCLS1 associated X-1
MGI:1346319

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Neutropenia	Acute lymphoblastic leukemia	Myelodysplasia
Disease(s) Associated with HAX1
severe congenital neutropenia 3

Mouse Phenotypes

thymus hypoplasia

decreased thymocyte number

decreased immature B cell number

decreased transitional stage T1 B cell number

decreased transitional stage T2 B cell number

decreased pro-B cell number

decreased double-positive T cell number

decreased bone marrow cell number

decreased neutrophil cell number

abnormal B cell number

decreased mature B cell number

decreased B-1a cell number

decreased marginal zone B cell number

increased follicular B cell number

decreased B cell number

decreased pre-B cell number

abnormal T cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

decreased single-positive T cell number

decreased lymphocyte cell number

decreased leukocyte cell number

decreased hematopoietic stem cell number

abnormal lymphocyte morphology

spleen hypoplasia

decreased IgG2a level

Availability

Mouse Genotype

Hax1^tm1.1Gach/Hax1^tm1.1Gach

Hax1^tm1Jni/Hax1^tm1Jni

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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